Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Blog  rightarrow anti-CHUK antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • ERVV-2 sirna blog
 • anti-STAT3 antibody blog
 • Tissue, Total Protein Adult Normal, Heart, Ventricle lysate blog
 • anti-CD28 antibody blog
 • anti-APOA5 antibody blog
 • Blvra recombinant protein blog
 • anti-CTSB antibody blog
 • IGFBP7 sirna blog
 • RFTN1 blocking peptide blog
 • TP53 blocking peptide blog
 • CYP24A1 elisa kit blog
 • anti-Scl-70 antibody blog
 • anti-MBD2 antibody blog
 • FAM69A sirna blog
 • Stomach lysate blog
 • CCL4 recombinant protein blog
 • anti-AMPH antibody blog
 • anti-RPL5 antibody blog
 • anti-Ku70 antibody blog
 • MAFF sirna blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • Smad3 (Ab-204) Antibody
 • Free Cholesterol (FCHOL) ELISA Kit
 • Shp-2 ELISA Kit
 • Heat Shock Protein 47 (HSP47) ELISA Kit
 • Interleukin 8 (IL-8) ELISA Kit
 • Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2Y12) ELISA Kit
 • Galectin 1 (GAL1) ELISA Kit
 • Acidic Fibroblast Growth Factor 1 (AFGF-1) ELISA Kit
 • Hepatitis B Virus E Antibody (HBEAB) ELISA Kit
 • Kruppel Like Factor 15 (KLF15) ELISA Kit
 • Adiponectin Receptor 2 (ADIPOR2) ELISA Kit
 • Glypican 2 (GPC2) ELISA Kit
 • True Insulin (TI) ELISA Kit
 • Leukocyte Antigen A (HLA-A) ELISA Kit
 downarrow more ...
separator

anti-CHUK antibody product blog

separator
Posted on 2013-12-16 19:33:25 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Antibody; Polyclonal Antibody; anti-CHUK antibody; CHUK; IkB alpha;
separator
The CHUK chuk (Catalog #MBS625007) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IkB alpha, phosphorylated (Ser32/Ser36) (NF-kappa-B Inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major Histocompatibility Complex Enhancer-binding Protein MAD3, NFKBIA, IKBA, MAD3, NFKBI) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IkB alpha can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry:1:50-1:100. Researchers should empirically determine the suitability of the CHUK chuk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CHUK chuk product has the following accession number(s) (GI #62241001) (NCBI Accession #NP_001269.3) (Uniprot Accession #O15111). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Three major forms of IKB like molecules have been identified and each is characterised by multiple copies of ankyrin repeats. IKB alpha and IKB beta appear to be the major regulatory forms of IKB in most cells. These proteins interact with p65 or cRel containing forms of NFkB and block nuclear import by masking the nuclear localisation sequences of NFkB. The activation of NFkB involves the inducible phosphorylation and subsequent degradation of IKB. Immunoblotting easily detects the hyperphosphorylated forms of IKB alpha, but not phosphorylated IKB beta. Interestingly, IKB alpha and IKB beta mediate different NFkB responses. IkB alpha appears to control more transient activation of NFkB in response to an inducer, while IKB beta controls a persistent response. Bcl3 interacts with p50 and p52 containing forms of NFkB, but rather than being an inhibitor it appears to function to stimulate transcription. The degradation of IKB is confirmed by immunoblotting.

CHUK chuk

Immunogen: Synthetic phosphopeptide corresponding to human IkB alpha around the phosphorylation site of serine 32/36 (H-D-SP-G-L-D-SP -M-K). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHUK are readily searchable from our website. Different antibodies against the same target such as CHUK may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions