anti-CHST5 antibody product blog
Tags: Antibody; Polyclonal Antibody; Chst5; anti-CHST5 antibody; Carbohydrate Sulfotransferase 5;
The CHST5 chst5 (Catalog #MBS621397) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Carbohydrate Sulfotransferase 5 (CHST5, Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5, ALYE870, FLJ22167, GlcNAc6ST-3, GST4-alpha, hIGn6ST, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, MGC74625, PRO1886) reacts with Mouse and may cross-react with other species as described in the data sheet.Suitable for use in Peptide ELISA.
Dilution: Peptide ELISA: 1:32,000. Researchers should empirically determine the suitability of the CHST5 chst5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CHST5 chst5 product has the following accession number(s) (GI #21362052) (NCBI Accession #NP_078809.2) (Uniprot Accession #Q9GZS9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CHST5 (Carbohydrate sulfotransferase 5; also GlcNAc6ST-3, I-GlcNAc6ST and GST4 alpha) is likely a 53-56kD member of the sulfotransfease family of enzymes. It is a Golgi-embedded enzyme that is found in T cells, B cells and intestinal epithelium. It appears to act only on short carbohydrates and transfers sulfate to position #6 of mucin-associated GlcNAc. Human CHST5 is a 390aa type II transmembrane protein. It contains a short cytoplasmic segment (aa1-9) and a long luminal domain (aa28-390) that contains an enzymatic region (aa180-358). There is one alternate start site that is 22aa upstream of the standard site. Humans have a GST4-alpha and -beta gene, the result of gene duplication. Over aa28-390, these two gene products share 87% aa identity. Mouse has only one GST4 gene, and it is functionally related to human GST4- beta. Over aa 28-390, human GST4-alpha/CHST5 is 78% aa identical to mouse GST4.
Immunogen: Synthetic peptide corresponding to C-DSFKWASSTEKQPE from the C Terminus of mouse Carbohydrate Sulfotransferase 5 (NP_064334.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CHST5 are readily searchable from our website. Different antibodies against the same target such as CHST5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Neoplasms are some of the diseases may be linked to Carbohydrate Sulfotransferase 5 (CHST5, Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5, ALYE870, FLJ22167, GlcNAc6ST-3, GST4-alpha, hIGn6ST, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, MGC74625, PRO1886).