anti-CEA antibody product blog
Tags: Antibody; CEA; Monoclonal Antibody; anti-CEA antibody;
The CEA ceacam5 (Catalog #MBS850266) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CEA Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CEA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the CEA ceacam5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CEA ceacam5 product has the following accession number(s) (GI #98986445) (NCBI Accession #NP_004354.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CEA Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using CEA mAb against HEK293 (1) and CEA-hIgGFc transfected HEK293 (2) cell lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues (left) and stomach cancer tissues (right) using CEA mouse mAb with DAB staining.)
Testing Data
Carcino Embryonic Antigen (CEA) is synthesised during development in the fetal gut, and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and an useful tumor marker for adenocarcinoma.Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
Immunogen: Purified recombinant fragment of human CEA expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CEA are readily searchable from our website. Different antibodies against the same target such as CEA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CEA also interacts with the following gene(s): CEACAM6, HNRNPM, RAB11A, VIPAR, VPS33B. Brain, Cervix, Intestine, Kidney, Lung, Muscle, Ovary, Pancreas, Stomach, Thyroid tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms are some of the diseases may be linked to CEA Antibody.