anti-CDK9 antibody product blog
Tags: Antibody; CDK9; Monoclonal Antibody; anti-CDK9 antibody;
The CDK9 cdk9 (Catalog #MBS850556) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CDK9 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CDK9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the CDK9 cdk9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CDK9 cdk9 product has the following accession number(s) (GI #4502747) (NCBI Accession #NP_001252.1) (Uniprot Accession #P50750). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CDK9 Antibody with the following immunoassay(s):
Testing Data (Figure 1: Western blot analysis using CDK9 mouse mAb against Jurkat (1), A431 (2) and HEK293 (3) cell lysate.)
Testing Data #2 (Figure 2: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues (left) and rectum cancer tissues (right) using CDK9 mouse mAb with DAB staining.)
Testing Data #3
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.
Immunogen: Purified recombinant fragment of human CDK9 expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CDK9 are readily searchable from our website. Different antibodies against the same target such as CDK9 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Cell Transformation, Neoplastic, Drug Toxicity, Heart Diseases, Hypertrophy, Immune System Diseases, Inflammation, Lung Diseases, Necrosis, Neoplasms are some of the diseases may be linked to CDK9 Antibody.