|The Cd99 cd99 (Catalog #MBS611785) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Paired Immunoglobulin-Like Type 2 Receptor-Ligand (PILR-L, CD99, MIC2) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Paired Immunoglobulin-Like Type 2 Receptor-Ligand can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Western Blot: This antibody can be used at 0.1-0.2ug/ml with the appropriate secondary reagents to detect mouse PILR-L. The detection limit for rmPILR-L is approximately 2 ng/lane under non-reducing and reducing conditions, respectively., Direct ELISA: This antibody can be used at 0.5-1.0ug/ml with the appropriate secondary reagents to detect mouse PILR-L. The detection limit for rmPILR-L is approximately 0.1 ng/well. In this format, this antibody shows less than 1% crossreactivity with rmPILR- and rmPILR-., Optimal dilutions should be determined by each laboratory for each application. Researchers should empirically determine the suitability of the Cd99 cd99 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Cd99 cd99 product has the following accession number(s) (GI #45330743) (Uniprot Accession #Q8VCN6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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PILR-L (also known as CD99 and MIC2) is a 125 amino acid, 24-30 kD glycosylated transmembrane glycoprotein expressed as a homodimer on the surface of endothelial, T and B cells, monocytes and stem cells. PILR-L has been implicated in processes like homotypic cell adhesion, diapedesis and oncosupression. The extracellular domain of the mouse PILR-L protein used as immunogen is 45% identical to the human counterpart.
Immunogen: NS0-derived rmPILR-L (aa25-138). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Cd99 are readily searchable from our website. Different antibodies against the same target such as Cd99 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Kidney Diseases, Lung Diseases, Lung Neoplasms, Lymphoma, Neoplasms, Pain, Rhabdomyosarcoma, Skin Diseases, Skin Neoplasms, Translocation, Genetic are some of the diseases may be linked to Paired Immunoglobulin-Like Type 2 Receptor-Ligand (PILR-L, CD99, MIC2). Brain, Connective Tissue, Embryonic Tissue, Eye, Intestine, Joint, Kidney, Liver, Pancreas, Testis tissues are correlated with this protein.