anti-CD80 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD80; anti-CD80 antibody;
The CD80 cd80 (Catalog #MBS830926) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CD80 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunofluorescence (IF).ELISA: 1:10,000
IF: 1:200-1:1000. Researchers should empirically determine the suitability of the CD80 cd80 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD80 cd80 product has the following accession number(s) (GI #119331110) (NCBI Accession #NP_001073207.1) (Uniprot Accession #Q5F3J1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD80 antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using anti-CD80 antibody)
Mouse monoclonal CD80 antibody.
Biological Significance: CD80 is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. Cross-Reactivity: Human
Immunogen: CD80 antibody was raised in Mouse using a purified recombinant fragment of CD80 expressed in E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD80 are readily searchable from our website. Different antibodies against the same target such as CD80 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental are some of the diseases may be linked to CD80 antibody. CD80 also interacts with the following gene(s): CD274, CD28, CD40, CD86, CD8A, CTLA4, FGF7, IL10, MYC, PDCD1LG2. Blood, Bursa Of Fabricius, Muscle, Other, Ovary tissues are correlated with this protein.