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anti-CD8 antibody product blog

Posted on 2014-04-19 00:12:39 by mybiosource_staff
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Tags: Antibody; CD8; Monoclonal Antibody; anti-CD8 antibody;
The CD8 cd8a (Catalog #MBS684124) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti - CD8 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) - Formalin/Paraffin.
IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user. Researchers should empirically determine the suitability of the CD8 cd8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CD8 cd8a product has the following accession number(s) (GI #116035) (NCBI Accession #P01732.1) (Uniprot Accession #P01732). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti - CD8 with the following immunoassay(s):
IHC (CDS expression in T-Iymphocytes of the palatine tonsil. Formalin fixed, paraffin embedded human tissue (4 um section) stained with anti-CD8 monospecific clonal antibody.)

Immunogen: Peptide derived from C-terminal region of human CD8
Storage Buffer: 20 mM Tris-HCI, pH 8.0
Stabilizer: 20 mg/ml BSA. Preservative: 0.05% NaN3
Immunogen: Peptide derived from C-terminal region of human CD8. Antibody recognizes the epitope between Pro218 - Tyr234.
Positive control: human tonsil tissue
Cellular localization: membrane. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD8 are readily searchable from our website. Different antibodies against the same target such as CD8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CD8 also interacts with the following gene(s): CD3D, CD3E, CD4, CD8B, HLA-A, HLA-B, LCK. The following patways have been known to be associated with this gene. Carcinoma, Cerebral Infarction, Fibrosis, Hemorrhage, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to Anti - CD8. Blood, Brain, Connective Tissue, Intestine, Kidney, Liver, Lung, Spleen, Stomach, Thymus tissues are correlated with this protein.
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