anti-CD40 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD40; anti-CD40 antibody;
The CD40 cd40 (Catalog #MBS235347) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s CD40 can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, ELISA (EIA), Western Blot (WB).Immunohistology - Frozen: Maximum Dilution: 10.0ug/ml;
ELISA: Maximum Dilution: 1.0ug/ml;
Western Blotting: Maximum Dilution: 10.0ug/ml. Researchers should empirically determine the suitability of the CD40 cd40 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD40 cd40 product has the following accession number(s) (GI #4507581) (NCBI Accession #NP_001241.1) (Uniprot Accession #P25942). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse anti Human CD40 antibody, clone 3B2 recognizes human CD40, a type I transmembrane glycoprotein receptor and member of the TNF-receptor superfamily, primarily expressed by B cells and professional antigen-presenting cells (APCs), which plays a vital role in T cell-B cell interactions and in germinal centre B cell selection. CD40 is a co-stimulatory molecule which mediates its immunoregulatory effects through interaction with its ligand CD154 (CD40L, gp39), playing a role in B cell proliferation and memory development, Ig class switching, activation of APCs and subsequent cytokine production, and the expansion of antigen-specific CD4+ T cells.
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
Preparation: Purified IgG prepared by affinity chromatography on Protein A. Buffer Solution: Phosphate buffered saline
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD40 are readily searchable from our website. Different antibodies against the same target such as CD40 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Kidney, Liver, Lung, Lymph, Lymph Node, Skin, Tonsil tissues are correlated with this protein. Arthritis, Rheumatoid, Atherosclerosis, Cardiovascular Diseases, Disease Models, Animal, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to MOUSE ANTI HUMAN CD40. The following patways have been known to be associated with this gene. CD40 also interacts with the following gene(s): BIRC2, BIRC3, CD40LG, CD86, JAK3, TRAF1, TRAF2, TRAF3, TRAF6.