|The CD4 cd4 (Catalog #MBS533376) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD4 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CD4 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Western Blot (WB).
WB: 1:2000. Researchers should empirically determine the suitability of the CD4 cd4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD4 cd4 product has the following accession number(s) (GI #10835167) (NCBI Accession #NP_000607) (Uniprot Accession #P01730). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CD4 antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant CD4 protein (Right) or empty vector (Left) detected with CD4 antibody)
Mouse monoclonal CD4 antibody.
Biological Significance: Human CD4 is a cell surface glycoprotein of 55 kDa expressed on most thymocytes, on about two thirds of peripheral T cells, and on some monocyte macrophage lineage cells. CD4 interacts with MHC Class II molecules in an accessory role during foreign antigen recognition by T cells. The extracellular portion of CD4 is an array of four Ig-like domains. The amino terminal region of CD4 is a receptor for the HIV-1 viral protein gp120. Immunogen: CD4 antibody was raised in mouse using a full length recombinant protein of human CD4 (NP_000607) produced in HEK293T cells, as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD4 are readily searchable from our website. Different antibodies against the same target such as CD4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. AIDS-Related Opportunistic Infections, Carcinoma, Cardiovascular Diseases, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Pneumonia, Vascular Diseases are some of the diseases may be linked to CD4 antibody. Blood, Bone, Bone Marrow, Brain, Intestine, Liver, Lung, Lymph Node, Spleen, Thymus tissues are correlated with this protein.