anti-CD27 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD27; anti-CD27 antibody;
The CD27 cd27 (Catalog #MBS520087) is an Antibody produced from Armenian Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD27 FITC (Clone LG.3A10) (Armenian Hamster IgG1) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD27 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) (stimulating). Researchers should empirically determine the suitability of the CD27 cd27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The CD27 cd27 product has the following accession number(s) (GI #4507587) (NCBI Accession #NP_001233.1) (Uniprot Accession #P26842). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse CD27 FITC (Clone LG.3A10) (Armenian Hamster IgG1) with the following immunoassay(s):
Testing Data
anti-mouse CD27 Monoclonal Antibody is specific for the mouse CD27 receptor. CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both alphabeta and gammadelta T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events. This clone (LG.3A10) has been reported to work in Immunohistochemistry on frozen tissue sections, Flow Cytometry and in functional studies (stimulating).
Immunogen: MCD27 tag expressing clones AR0524 and AR0530
Donor: Armenian hamster spleen
Fusion Partner: SP2/0 Murine Myeloma Partner. Presentation: Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD27 are readily searchable from our website. Different antibodies against the same target such as CD27 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.