anti-CD14 antibody product blog
Tags: Antibody; Monoclonal Antibody; CD14; anti-CD14 antibody;
The CD14 ndufa2 (Catalog #MBS140130) is an Antibody and is intended for research purposes only. The product is available for immediate purchase.The CD14 ndufa2 product has the following accession number(s) (GI #297206774) (NCBI Accession #NP_001171941.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Introduction: CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen: Purified human B Cells Ig SubclassMouse IgG1.
Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator.
Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/106 cells. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD14 are readily searchable from our website. Different antibodies against the same target such as CD14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Heart, Muscle, Skin tissues are correlated with this protein. Leigh Disease, Nervous System Diseases are some of the diseases may be linked to Mouse Anti Human CD14. CD14 also interacts with the following gene(s): NDUFA6, NDUFA7, NDUFB8, NDUFV2. The following patways have been known to be associated with this gene.