anti-CD11c antibody product blog
Tags: Antibody; Monoclonal Antibody; CD11c; anti-CD11c antibody;
The CD11c itgax (Catalog #MBS690274) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The Hamster Anti-Mouse CD11c reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CD11c can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) - Paraffin, Flow Cytometry (FC/FACS), Immunoprecipitation (IP).FC: 1:100-1000
IP: 1:100
IHC (Paraffin): 1: 25-100
Optimal dilutions should be determined by each laboratory for each applications. Researchers should empirically determine the suitability of the CD11c itgax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CD11c itgax product has the following accession number(s) (GI #10946646) (NCBI Accession #NP_067309.1) (Uniprot Accession #Q9QXH4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Hamster Anti-Mouse CD11c with the following immunoassay(s):
Testing Data
Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.
Reconstitution: Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
Reconstitution buffer: PBS (sterile)
Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an armenian hamster) immunized with mouse lymphcytes.
Antigen: Mouse lymphocytes
Remarks: This antibody was selected for its ability to detectmouse CD11c. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD11c are readily searchable from our website. Different antibodies against the same target such as CD11c may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.