anti-CD11b antibody product blog
Tags: Antibody; Monoclonal Antibody; CD11b; anti-CD11b antibody;
The CD11b cd11b (Catalog #MBS140127) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase.The CD11b cd11b product has the following accession number(s) (GI #1616950) (NCBI Accession #AAB16869.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Introduction: Integrins are heterodimeric integral membrane proteins consisting of an ? chain and a ? chain. CD11b is an I-domain including ? integrin combines with the ? 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The ? M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen: Purified human PBL Monocytes.
Antibody Properties: Blocking and staining antibody. For staining, use 10 ul/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator.
Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10 ul/106 cells. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CD11b are readily searchable from our website. Different antibodies against the same target such as CD11b may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.