anti-CCR5 antibody product blog
Tags: Antibody; anti-CCR5 antibody; CCR5; Polyclonal Antibody;
The CCR5 ccr5 (Catalog #MBS242012) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal (IgG) to Human CCR5 reacts with HumanPredicted Reactivity: Chimpanzee, Orangutan, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s CCR5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA).
ELISA (1:100000), ICC (1:300), IHC-P (5 ug/ml), WB (1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CCR5 ccr5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CCR5 ccr5 product has the following accession number(s) (GI #4502639) (NCBI Accession #NP_000570.1) (Uniprot Accession #P51681). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat Polyclonal (IgG) to Human CCR5 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-CCR5 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
CCR5, a Chemokine Receptor, is a coreceptor for the human immunodeficiency virus-1 (HIV-1). HIV progression and resistance has been linked to variable CCR5 transcripts. For example, the disease progression from HIV-1 infection to AIDS appears to be slower in patients heterozygous for a 32-bp CCR5 deletion than in individuals homozygous for the normal CCR5 allele. The CCR5 gene is located near the genes for CCR2 and chemokine (C-C motif) receptor-like 2 on chromosome 3.
Target Species: Human
Immunogen Description: Synthetic peptide corresponding to aa 3-30 (Y3QVSSPIYDINYYTSEPCQKINVKQIAA30) of the C-terminal domain of human CCR5 (C-C chemokine receptor 5). Percent identity by BLAST analysis: Human (100%); Chimpanzee, Monkey (96%); Orangutan, Baboon (93%). Immunogen Type: Synthetic peptide
Immunogen: CCR5 antibody was raised against synthetic peptide corresponding to aa 3-30 (Y3QVSSPIYDINYYTSEPCQKINVKQIAA30) of the C-terminal domain of human CCR5 (C-C chemokine receptor 5). Percent identity by BLAST analysis: Human (100%); Chimpanzee, Monkey (96%); Orangutan, Baboon (93%); Gorilla (89%).
Antigen Modification: aa3-30. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCR5 are readily searchable from our website. Different antibodies against the same target such as CCR5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.