anti-CCND3 antibody product blog
Tags: Antibody; Monoclonal Antibody; CCND3; anti-CCND3 antibody;
The CCND3 ccnd3 (Catalog #MBS850720) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CCND3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CCND3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB: 1:500-1:2000
ELISA: 1:10000. Researchers should empirically determine the suitability of the CCND3 ccnd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CCND3 ccnd3 product has the following accession number(s) (GI #209862835) (NCBI Accession #NP_001129489.1) (Uniprot Accession #P30281). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CCND3 Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using CCND3 mouse mAb against NIH/3T3 (1) and Jurkat (2) cell lysate.)
Testing Data
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen: Purified recombinant fragment of human CCND3 expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CCND3 are readily searchable from our website. Different antibodies against the same target such as CCND3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CCND3 also interacts with the following gene(s): CDK4, CDK6, CDKN1A, CDKN1B, EIF3K, NCOA2, PCNA, RBL2, RUNX1, VDR. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Cell Transformation, Neoplastic, Drug Toxicity, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to CCND3 Antibody.