anti-CAV1 antibody product blog
Tags: Antibody; Polyclonal Antibody; CAV1; anti-CAV1 antibody; CAV1 / Caveolin 1;
The CAV1 cav1 (Catalog #MBS240039) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CAV1 / Caveolin 1 reacts with Gibbon, Chimpanzee, Gorilla, Human, MonkeyPredicted Reactivity: Orangutan, Guinea pig (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s CAV1 / Caveolin 1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (4 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the CAV1 cav1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CAV1 cav1 product has the following accession number(s) (GI #15451856) (NCBI Accession #NP_001744.2) (Uniprot Accession #Q03135). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human CAV1 / Caveolin 1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-CAV1 / Caveolin antibody IHC of human respiratory epithelium and alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Caveolin 1 (CAV1) is the main component of the caveolae plasma membranes found in most cell types. Caveolin 1 functions as a membrane adaptor to link integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. CAV1 may also be a tumor suppressor gene and a negative regulator of the Ras-p42/44 MAP kinase cascade.
Target Species: Human
Immunogen Description: Synthetic 16 amino acid peptide from N-terminus of human CAV1 / Caveolin. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (94%). Immunogen Type: Synthetic peptide
Immunogen: CAV1 / Caveolin 1 antibody was raised against synthetic 16 amino acid peptide from N-terminus of human CAV1 / Caveolin. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%); Orangutan, Guinea pig (94%); Mouse, Rat, Dog, Rabbit, Horse, Turkey, Chicken (88%); Galago, Ferret, Sheep, Cat, Bat, Bovine, Panda, Pig, Opossum, Armadillo, Lizard (81%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CAV1 are readily searchable from our website. Different antibodies against the same target such as CAV1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.