anti-CASP4 antibody product blog
Tags: Antibody; Polyclonal Antibody; CASP4 / Caspase 4; anti-CASP4 antibody; CASP4;
The CASP4 casp4 (Catalog #MBS240972) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human CASP4 / Caspase 4 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s CASP4 / Caspase 4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the CASP4 casp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CASP4 casp4 product has the following accession number(s) (GI #4502577) (NCBI Accession #NP_001216.1) (Uniprot Accession #P49662). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human CASP4 / Caspase 4 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-CASP4 / Caspase 4 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC) (Anti-CASP4 / Caspase 4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB) (Western blot of caspase-4 in Ramos cells with caspase-4 antibody at (A) 0.5 and (B) 1 g/ml.)
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18.
Target Species: Human
Immunogen Description: Synthetic peptide from human CASP4 / Caspase 4. Immunogen Type: Synthetic peptide
Immunogen: CASP4 / Caspase 4 antibody was raised against synthetic peptide from human CASP4 / Caspase 4. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CASP4 are readily searchable from our website. Different antibodies against the same target such as CASP4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.