anti-C7 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-C7 antibody;
The C7 c7 (Catalog #MBS212935) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s C7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assays (FN), Western Blot (WB). Researchers should empirically determine the suitability of the C7 c7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The C7 c7 product has the following accession number(s) (GI #45580688) (NCBI Accession #NP_000578.2) (Uniprot Accession #P10643). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse anti Human C7 antibody, clone 030-113.7.5.4 recognises complement component 7 (C7), a 110 kDa glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Mouse anti Human C7 antibody, clone 030-113.7.5.4 does not recognie membrane bound complement membrane attack complex. Mouse anti Human C7 antibody, clone 030-113.7.5.4 inhibits lysis of sensitised sheep erythrocytes. Removal of Sodium Azide is recommended prior to use in functional assays. MyBioSource recommend the use of EQU003 for this purpose.
Perservative Stabilisers: 0.1% Sodium Azide (NaN3)
Preparation: Purified IgG prepared by affinity chromatography on Protein A. Buffer Solution: Borate buffered saline
Target Species: Human
Immunogen: Purified human C7. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C7 are readily searchable from our website. Different antibodies against the same target such as C7 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Brain, Ganglia, Heart, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein. C7 also interacts with the following gene(s): C8A, C8B, C8G, CLU, PLG. Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Hemolysis, Hemorrhage, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis are some of the diseases may be linked to MOUSE ANTI HUMAN C7.