anti-C1QB antibody product blog
Tags: Antibody; Polyclonal Antibody; Complement C1q; anti-C1QB antibody; C1QB;
The C1QB c1qb (Catalog #MBS535019) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Complement C1q can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the C1QB c1qb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The C1QB c1qb product has the following accession number(s) (GI #87298828) (NCBI Accession #NP_000482.3) (Uniprot Accession #P02746). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rabbit polyclonal Complement C1q antibody.
Biological Significance: The C1q complex is potentially multivalent for attachment to the complement fixation sites of immunoglobulin. The sites are on the CH2 domain of IgG and probably on the CH4 domain of IgM. The appropriate peptide sequence of the complement fixing site might become exposed following complexing of the immunoglobulin, or the sites might always be available, but might require multiple attachment by C1q with critical geometry in order to achieve the necessary avidity. Biohazard Information: Donor samples were tested and found to be negative for HBsAg, anti-HIV 1 & 2 and anti-HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Immunogen: Compeltment C1q antibody was raised in rabbit using complement C1q as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing C1QB are readily searchable from our website. Different antibodies against the same target such as C1QB may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. C1QB also interacts with the following gene(s): C1QA, C1QC, C1R, C1S, C4B, CRP, CSTB, SERPING1. The following patways have been known to be associated with this gene. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Learning Disorders, Liver Diseases, Memory Disorders, Necrosis, Nervous System Diseases, Poisoning are some of the diseases may be linked to Complement C1q antibody. Bone, Brain, Connective Tissue, Eye, Kidney, Liver, Lung, Mouth, Spleen, Vascular tissues are correlated with this protein.