|The c-met met (Catalog #MBS213448) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI HUMAN c-met reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s c-met can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
ELISA: Maximum Dilution: 1/1,000;
Western Blotting: Minimum Dilution: 1/100; Maximum Dilution: 1/500. Researchers should empirically determine the suitability of the c-met met for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The c-met met product has the following accession number(s) (GI #42741655) (NCBI Accession #NP_000236.2) (Uniprot Accession #P08581). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MBS213448 recognises c-Met, a receptor tyrosine kinase also known as Hepatocyte growth factor receptor or HGFR. Binding HGF leads to autophosphorylation of c-Met and the activation of signal transduction pathways.
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
Preparation: Purified IgG prepared by affinity chromatography on Protein G. Immunogen: Purified recombinant protein representing the catalytic domain of human Met/HGFR
Buffer Solution: Phosphate buffered saline
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing c-met are readily searchable from our website. Different antibodies against the same target such as c-met may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Cardiovascular Diseases, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Lung Neoplasms, Schizophrenia are some of the diseases may be linked to MOUSE ANTI HUMAN c-met. Bone, Brain, Eye, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. c-met also interacts with the following gene(s): CBL, CTNNB1, GAB1, GRB2, HGF, PAX3, PTPN1, PTPN11, PTPRJ, UBC.