anti-Bst2 antibody product blog
Tags: Antibody; Polyclonal Antibody; Bst2; anti-Bst2 antibody;
The Bst2 bst2 (Catalog #MBS150243) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Bst2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Bst2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Bst2 antibody can be used for detection of Bst2 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the Bst2 bst2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Bst2 bst2 product has the following accession number(s) (GI #56971124) (NCBI Accession #AAH87949) (Uniprot Accession #Q8R2Q8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bst2 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of Bst2 in Daudi cell lysate with Bst2 antibody at (A) 1 and (B) 2 μg/mL.)
Bst2 Antibody: Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues. The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line, suggesting that this protein is involved in pre-B-cell growth. Later experiments also showed it to be upregulated in several myeloma cells. More recently, Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu. While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release. This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS.
Conjugate: Unconjugated
Immunogen: Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2.
Buffer: Bst2 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Bst2 are readily searchable from our website. Different antibodies against the same target such as Bst2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.