anti-BMPR2 antibody product blog
Tags: Antibody; BMPR2; Monoclonal Antibody; anti-BMPR2 antibody;
The BMPR2 bmpr2 (Catalog #MBS850312) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The BMPR2 Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s BMPR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the BMPR2 bmpr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BMPR2 bmpr2 product has the following accession number(s) (GI #15451916) (NCBI Accession #NP_001195.2) (Uniprot Accession #Q13873). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BMPR2 Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using BMPR2 mouse mAb against Hela (1), A431 (2), NIH/3T3 (3), Cos7 (4) and PC-12 (5) cell lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded muscle tissues (left) and kidney cancer tissues (right) using BMPR2 mouse mAb with DAB staining.)
Testing Data
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq).
Immunogen: Purified recombinant fragment of human BMPR2 expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BMPR2 are readily searchable from our website. Different antibodies against the same target such as BMPR2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.