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anti-Blimp-1 antibody product blog

Posted on 2013-08-06 11:33:23 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; Blimp-1; anti-Blimp-1 antibody;
The Blimp-1 blimp-1 (Catalog #MBS600028) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Blimp-1 (BLIMP 1, BLIMP1, B Lymphocyte Induced Maturation Protein 1, Positive Regulatory Domain I Binding Factor 1, PR Domain Containing 1, PRDI BF1, PRDM1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Blimp-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Dilution: Immunofluorescence/Immunocytochemistry: 1:50-1:200
Flow Cytometry: 8ug/ml where cells are used at 2x10e6/ml
Western Blot: 1:1000
Immunohistochemistry (Paraffin): 1:200. Researchers should empirically determine the suitability of the Blimp-1 blimp-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Blimp-1 blimp-1 product has the following accession number(s) (GI #21358403) (NCBI Accession #NP_647982.1) (Uniprot Accession #Q9VRN4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Blimp-1 (B lymphocyte maturation protein-1) is a nuclear protein with five zinc fingers in its carboxy terminus. It is a transcriptional repressor that is both required and sufficient to trigger terminal differentiation of B lymphocytes and monocyte/macrophages. Blimp-1 is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. It has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

Blimp-1 blimp-1

Immunogen: A fragment of the mouse Blimp-1 (residues 199-409).
Cellular Localization: Nuclear. Positive Control: P3X (murine plasmocytoma) cell lysates. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Blimp-1 are readily searchable from our website. Different antibodies against the same target such as Blimp-1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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