|The BK Beta3a K+ Channel n/a (Catalog #MBS190560) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-BK Beta3a K+ Channel Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. MyBioSource\'s BK Beta3a K+ Channel can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence.
Immunoblotting: use at 1ug/ml. A band of ~32kDa is detected. Immunohistochemistry and Immunocytochemistry: use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Adult rat brain lysate. Researchers should empirically determine the suitability of the BK Beta3a K+ Channel n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-BK Beta3a K+ Channel Monoclonal Antibody with the following immunoassay(s):
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. BK channels contribute to electrical impulses, proper signal transmission, and regulation of neurotransmitter release. Research suggests that distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia.
Antigen: Fusion protein corresponding to aa 1-49 (unique N-terminus) of mouse BK Beta3a (accession no. XP_989315). This sequence is 86% homologous with human BK Beta3a. Dilution Instructions: Dilute in PBS or medium which is identical to that used in the assay system. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BK Beta3a K+ Channel are readily searchable from our website. Different antibodies against the same target such as BK Beta3a K+ Channel may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.