|The BDNF bdnf (Catalog #MBS535248) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The BDNF antibody reacts with To be determined by end-user and may cross-react with other species as described in the data sheet. MyBioSource\'s BDNF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the BDNF bdnf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BDNF bdnf product has the following accession number(s) (GI #179407) (NCBI Accession #AAA96140.1) (Uniprot Accession #P23560). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BDNF antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (BDNF was detected in perfusion fixed frozen sections of rat spinal cord (dilution 7 ugmL) overnight at 4 deg C. Tissue was stained (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to spinal cord dorsal horn.)
Chicken polyclonal BDNF antibody.
Biological Significance: Brain-derived Neurotrophic Factor (BDNF) is a member of the NGF family of neurotrophic factors. BDNF, NGF, NT-3, and NT-4/5 are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. High levels of expression of BDNF have been detected in the hippocampus, cerebellum, fetal eye, and placenta. Immunogen: BDNF antibody was raised in chicken using recombinant human brain-derived neurotrophic factor as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BDNF are readily searchable from our website. Different antibodies against the same target such as BDNF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Body Weight, Brain Injuries, Brain Ischemia, Cognition Disorders, Depressive Disorder, Inflammation, Memory Disorders, Nerve Degeneration, Nervous System Diseases, Schizophrenia are some of the diseases may be linked to BDNF antibody. Adrenal Gland, Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Liver, Lung, Skin, Thyroid tissues are correlated with this protein. The following patways have been known to be associated with this gene.