anti-BCL2L11 antibody product blog
Tags: Antibody; BIM; Monoclonal Antibody; BCL2L11; anti-BCL2L11 antibody;
The BCL2L11 bcl2l11 (Catalog #MBS150042) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Bim Antibody [1C2H4] reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Bim can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF).Bim antibody can be used for detection of Bim by Western blot at 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the BCL2L11 bcl2l11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BCL2L11 bcl2l11 product has the following accession number(s) (GI #20336315) (NCBI Accession #NP_619527) (Uniprot Accession #O43521). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Bim Antibody [1C2H4] with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of 5 ng of Bim recombinant protein with Bim antibody at 1 μg/mL.)
Immunocytochemistry (IHC) (Immunocytochemistry of Bim in K562 cells with Bim antibody at 10 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of Bim in K562 cells with Bim antibody at 20 μg/mL.)
Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Conjugate: Unconjugated
Immunogen: Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Buffer: Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BCL2L11 are readily searchable from our website. Different antibodies against the same target such as BCL2L11 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.