anti-Bcl-3 antibody product blog
Tags: Antibody; Monoclonal Antibody; Bcl-3; anti-Bcl-3 antibody;
The Bcl-3 bcl3 (Catalog #MBS520010) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse Bcl-3, Biotin (Clone Ham 150-3.5) (hamster IgG) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Bcl-3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Bcl-3 bcl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The Bcl-3 bcl3 product has the following accession number(s) (GI #114870) (NCBI Accession #P20749.1) (Uniprot Accession #P20749). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse Bcl-3, Biotin (Clone Ham 150-3.5) (hamster IgG) with the following immunoassay(s):
Testing Data
anti-mouse Bcl-3 monoclonal antibody reacts with both mouse and human Bcl-3 (B-cell Leukemia/lymphoma 3). The proto-oncoprotein Bcl-3 is a member of the IkappaB family and is present predominantly in the nucleus. This protein has been shown to function as a transcriptional co-activator for homodimers of NF-kappaB p50 and p50B. In addition to p50 and p52, Bcl-3 also associates with nuclear proteins Jab1, Pirin, Tip60 and Bard1. The mouse Bcl-3 coding region exhibits 80% homology with human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs. Applications for this clone include Western Blotting, ELISA and flow cytometry.
Immunogen: recombinant Bcl-3-6-histidine tag
Donor: Armenian Hamster
Fusion Partner: SP2/0 myeloma. Presentation: 100 ug or 300 ug Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Bcl-3 are readily searchable from our website. Different antibodies against the same target such as Bcl-3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lymph Node, Placenta, Skin, Spleen, Thyroid tissues are correlated with this protein.