anti-b-Amyloid antibody product blog
Tags: Antibody; Polyclonal Antibody; b-Amyloid; anti-b-Amyloid antibody;
The b-Amyloid n/a (Catalog #MBS610472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The b-Amyloid, 36-42aa reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s b-Amyloid can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Radioimmunoassay (RIA), Gel Shift Assay (GS/EMSA).Suitable for use in RIA, ELISA, and Dot Blot.
Dilution: Dot Blot: 0.05-1mg/ml. Researchers should empirically determine the suitability of the b-Amyloid n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Alzheimer\'s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major component of these plaques is Ab peptide (b-amyloid), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein (APP). Increased release of the \'longer forms\' of Ab peptide, Ab42 or Ab43, which have a greater tendency to aggregate than Ab40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles, or may involve other, still undiscovered, factors. Many researchers theorize that this increased release of Ab42/Ab43 leads to the abnormal deposition of Ab and the associated neurotoxicity in the brains of affected individuals.
Immunogen: b-amyloid 42 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing b-Amyloid are readily searchable from our website. Different antibodies against the same target such as b-Amyloid may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.