anti-APRIL, ED2 antibody product blog
Tags: Antibody; Polyclonal Antibody; APRIL, ED2; anti-APRIL, ED2 antibody;
The APRIL, ED2 n/a (Catalog #MBS612868) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APRIL, ED2 (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s APRIL, ED2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1-4ug/ml
Immunohistochemistry: 10ug/ml. Researchers should empirically determine the suitability of the APRIL, ED2 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the APRIL, ED2 (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13) with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemical analysis of MBS612868.)
Western Blot (WB) (Western Blot analysis of MBS612868.)
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identi ed by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF-and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand 1a) in human and mouse (1-4). Two receptors for APRIL were recently identi ed and designated TACI and BCMA (5-7). APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death (1-7). APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer (8,9).
Immunogen: Synthetic peptide corresponding to amino acids within an extracellular domain of human APRIL (1-3). Positive Control: J9000: Jurkat cell lysate. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing APRIL, ED2 are readily searchable from our website. Different antibodies against the same target such as APRIL, ED2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.