|The APOC3 apoc3 (Catalog #MBS242423) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal (IgG) to Human APOC3 / Apolipoprotein C III reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s APOC3 / Apolipoprotein C III can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA).
ELISA (1:5000 - 1:10000), IHC-P (2.5 ug/ml), IP (1:100), WB (1:500 - 1:5000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the APOC3 apoc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The APOC3 apoc3 product has the following accession number(s) (GI #4557323) (NCBI Accession #NP_000031.1) (Uniprot Accession #P02656). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat Polyclonal (IgG) to Human APOC3 / Apolipoprotein C III with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-APOC3 / Apolipoprotein CIII antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
Target Species: Human
Immunogen Description: Synthetic full-length Apolipoprotein Type C-III. Immunogen: APOC3 / Apolipoprotein C III antibody was raised against synthetic full-length Apolipoprotein Type C-III. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing APOC3 are readily searchable from our website. Different antibodies against the same target such as APOC3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. APOC3 also interacts with the following gene(s): APOA1, APOA2, APOA4, APOA5, APOB, APOC2, APOE, LPL, PPARA, PPARG.