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anti-AICAR antibody product blog

Posted on 2015-02-20 18:41:12 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; AICAR / ATIC; anti-AICAR antibody; AICAR;
The AICAR atic (Catalog #MBS245051) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone F38 P7 H9] (IgG1) to Human AICAR / ATIC reacts with Gibbon, Bovine, Dog, Drosophila, Xenopus, Gorilla, Horse, Human, Monkey, Orangutan, Pig, Rabbit
Predicted Reactivity: Mouse, Rat, Bat, Hamster, Chicken, Insect (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s AICAR / ATIC can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).
IHC-P (15 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the AICAR atic for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The AICAR atic product has the following accession number(s) (GI #20127454) (NCBI Accession #NP_004035.2) (Uniprot Accession #P31939). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone F38 P7 H9] (IgG1) to Human AICAR / ATIC with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-ATIC antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)
Immunohistochemistry (IHC) AICAR.

Western Blot (WB) (Western blot of extract from HeLa cells using anti-ATIC, clone F38P7H9.)
Western Blot (WB) AICAR.

Target Species: Human
Immunogen Description: Synthetic peptide from human ATIC. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Dog, Bovine, Horse, Rabbit, Pig, Xenopus, Drosophila, Beetle (100%). Immunogen Type: Synthetic peptide
Immunogen: AICAR / ATIC antibody was raised against synthetic peptide from human ATIC. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Dog, Bovine, Horse, Rabbit, Pig, Xenopus, Drosophila, Beetle (100%); Mouse, Rat, Hamster, Bat, Opossum, Turkey, Chicken, Platypus, Stickleback, Mosquito (90%); Elephant, Salmon, Zebrafish, Seq squirt, Sea anemone, Ant, Nematode (80%). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing AICAR are readily searchable from our website. Different antibodies against the same target such as AICAR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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