anti-14-3-3 beta antibody product blog
Tags: Antibody; 14-3-3 beta; Monoclonal Antibody; anti-14-3-3 beta antibody;
The 14-3-3 beta ywhab (Catalog #MBS834603) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s 14-3-3 beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB: 1:2000. Researchers should empirically determine the suitability of the 14-3-3 beta ywhab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The 14-3-3 beta ywhab product has the following accession number(s) (GI #21328448) (NCBI Accession #NP_647539.1) (Uniprot Accession #P31946). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the 14-3-3 beta antibody with the following immunoassay(s):
Western Blot (WB) ()
Mouse monoclonal 14-3-3 beta antibody.
Biological Significance: 14-3-3, a family of acidic and soluble proteins, highly conserved in amino acid sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms (beta, gamma, epsilon, eta, zeta, omega and t/?) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cup-shaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal trans-duction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders. Cross-Reactivity: Human, Mouse, Rat
Immunogen: 14-3-3 beta antibody was raised in Mouse using a recombinant human protein purified from E Coli as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing 14-3-3 beta are readily searchable from our website. Different antibodies against the same target such as 14-3-3 beta may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. 14-3-3 beta also interacts with the following gene(s): CDC25B, CDC25C, FOXO3, HDAC4, TSC2. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Cardiovascular Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Neurodegenerative Diseases, Seizures are some of the diseases may be linked to 14-3-3 beta antibody.