AMOT blocking peptide product blog
Tags: Blocking Peptide; AMOT; AMOT blocking peptide; AMOT (S1041);
The AMOT amot (Catalog #MBS9225261) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The AMOT amot product has the following accession number(s) (GI #74753814) (NCBI Accession #Q4VCS5.1) (Uniprot Accession #Q4VCS5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Cellular Location: Cell junction, tight junction. Note: Localized on the cell surface May act as a transmembrane protein. Tissue Location: Expressed in placenta and skeletal muscle. Found in the endothelial cells of capillaries as well as larger vessels of the placenta. The following patways have been known to be associated with this gene. Breast Neoplasms, Cell Transformation, Neoplastic, Embryo Loss, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental are some of the diseases may be linked to Phospho-AMOT(S1041) Antibody Blocking peptide. AMOT also interacts with the following gene(s): ARHGAP17, INADL, LATS1, LATS2, MPDZ, MPP5, NF2, YAP1. Brain, Connective Tissue, Kidney, Lung, Lymph Node, Mammary Gland, Muscle, Ovary, Placenta, Skin tissues are correlated with this protein.