|The ALPP alpp (Catalog #MBS653808) is an Enzyme produced from Human placenta and is intended for research purposes only. The product is available for immediate purchase.
The ALPP alpp product has the following accession number(s) (GI #178464) (NCBI Accession #AAA51706.1) (Uniprot Accession #P05187). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Phosphatase, Alkaline, Placental (Alkaline Phosphatase, Placental Type, Alkaline Phosphatase Regan isozyme, ALP, FLJ61142, PALP, Placental Alkaline Phosphatase 1, PLAP, PLAP-1)
Placental alkaline phosphatase (PLAP) is a membrane-associated sialoglycoprotein enzyme normally present at high concentration in syncytiotrophoblasts within the placenta during the third trimester of gestation. The expression of PLAP was originally thought to be restricted to term placenta but a human PLAP-like variant has been described which shares more than 85% homology with PLAP itself. PLAP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It is also commonly expressed in germ cell tumors and more recently described in seminomas.
ALPP also interacts with the following gene(s): PTS. The following patways have been known to be associated with this gene. Amniotic Fluid, Heart, Intestine, Placenta, Uterus tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Disorders of Sex Development, Liver Diseases, Lung Diseases, Mental Disorders, Necrosis, Neoplasms, Nervous System Diseases, Pain are some of the diseases may be linked to Phosphatase, Alkaline, Placental (Alkaline Phosphatase, Placental Type, Alkaline Phosphatase Regan isozyme, ALP, FLJ61142, PALP, Placental Alkaline Phosphatase 1, PLAP, PLAP-1).