|The AFP afp (Catalog #MBS537816) is a Native Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. The AFP protein reacts with >95% by PAGE.
Affinity purified. and may cross-react with other species as described in the data sheet. MyBioSource\'s AFP can be used in a range of immunoassay formats including, but not limited to, Control. Researchers should empirically determine the suitability of the AFP afp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AFP afp product has the following accession number(s) (GI #178236) (NCBI Accession #AAB58754.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including AFP are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Source: AFP cell line
Contaminants: None deteected by IEP and PAGE
Protein Type: Native
Biological Significance: Alpha-fetoprotein (AFP) is a protein that in humans is encoded by the AFP gene. Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Biohazard Information: The cell line supernant tested negative for HCV Ab, HIV-1/2 Ab, HIV-1 and HBsAg and HCV by Nat per current FDA methods. Please note that the samples tested were Cell Culture Supernatants, not Serum and not appropiate for use in these Assays. Handle as through infectious. AFP also interacts with the following gene(s): CEBPA, EFNA1, FOXA1, FOXA3, FOXM1, JUN, MYC, TP53, UBC, ZFHX3. Carcinoma, Hepatocellular, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Liver Neoplasms, Experimental, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Stomach Neoplasms are some of the diseases may be linked to AFP protein. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Placenta, Uterus, Vascular tissues are correlated with this protein.