|The AFP afp (Catalog #MBS537816) is a Native Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s AFP can be used in a range of immunoassay formats including, but not limited to, Control. Researchers should empirically determine the suitability of the AFP afp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The AFP afp product has the following accession number(s) (GI #178236) (NCBI Accession #AAB58754.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including AFP are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Source Note: AFP cell line
Protein Type: Native
Biological Significance: Alpha-fetoprotein (AFP) is a protein that in humans is encoded by the AFP gene. Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Carcinoma, Hepatocellular, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Liver Neoplasms, Experimental, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Stomach Neoplasms are some of the diseases may be linked to AFP protein. Blood, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Placenta, Uterus, Vascular tissues are correlated with this protein. AFP also interacts with the following gene(s): CEBPA, EFNA1, FOXA1, FOXA3, FOXM1, JUN, MYC, TP53, UBC, ZFHX3. The following patways have been known to be associated with this gene.