ADM blocking peptide product blog
Tags: Blocking Peptide; ADM; ADM blocking peptide;
The ADM adm (Catalog #MBS9225469) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ADM adm product has the following accession number(s) (GI #461474) (NCBI Accession #P35318.1) (Uniprot Accession #P35318). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Cellular Location: Secreted. Tissue Location: Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues. ADM also interacts with the following gene(s): ADM2, AVP, CALCA, CALCB, CALCRL, EDN1, IAPP, NPS, VIP. The following patways have been known to be associated with this gene. Breast Neoplasms, Cardiovascular Diseases, Heart Diseases, Liver Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Pain are some of the diseases may be linked to ADM Antibody (Center) Blocking Peptide. Blood, Bone, Brain, Heart, Liver, Lung, Mouth, Muscle, Skin, Vascular tissues are correlated with this protein.