ACVRL1 blocking peptide product blog
Tags: Blocking Peptide; ACVRL1; ACVRL1 blocking peptide;
The ACVRL1 acvrl1 (Catalog #MBS9229201) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ACVRL1 acvrl1 product has the following accession number(s) (GI #3915750) (NCBI Accession #P37023.2) (Uniprot Accession #P37023). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Cellular Location: Membrane; Single-pass type I membrane protein. Breast Neoplasms, Cardiovascular Diseases, Fibrosis, Heart Diseases, Hypertension, Inflammation, Liver Diseases, Lung Diseases, Lung Neoplasms, Telangiectasia, Hereditary Hemorrhagic are some of the diseases may be linked to ACVRL1 Blocking Peptide (N-term). The following patways have been known to be associated with this gene. Bone, Brain, Connective Tissue, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein.