ACVR1 blocking peptide product blog
Tags: ACVR1; Blocking Peptide; ACVR1 blocking peptide; Activin (ACVR1);
The ACVR1 acvr1 (Catalog #MBS9226588) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ACVR1 acvr1 product has the following accession number(s) (GI #462447) (NCBI Accession #Q04771.1) (Uniprot Accession #Q04771). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity).
Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location: Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells. ACVR1 also interacts with the following gene(s): ACVR2A, BMP2, BMP4, BMP7, FKBP1A, INHBA, SMAD1, SMAD2, SMAD5, SMAD9. Blood, Bone, Brain, Connective Tissue, Embryonic Tissue, Heart, Lung, Muscle, Ovary, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Astrocytoma, Breast Neoplasms, Death, Glioma, Hypertension, Inflammation, Myositis Ossificans, Nervous System Diseases, Vascular Diseases are some of the diseases may be linked to Activin Receptor Type IA (ACVR1) Antibody (Center N153) Blocking peptide.